C24-propyl sterols and derivatives
Beta-Sitosterol From Soybeans Practical MP Biomedicals
CAS: 83-46-5 Molecular Formula: C29H50O Molecular Weight (g/mol): 414.718 InChI Key: KZJWDPNRJALLNS-VJSFXXLFSA-N Synonym: beta-sitosterol,sitosterol,cupreol,quebrachol,22,23-dihydrostigmasterol,azuprostat,triastonal,cinchol,rhamnol,harzol PubChem CID: 222284 ChEBI: CHEBI:27693 IUPAC Name: (3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol SMILES: CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C
Phytosterols, Practical Grade, MP Biomedicals™
CAS: 83-46-5 Molecular Formula: C29H50O Molecular Weight (g/mol): 414.718 InChI Key: KZJWDPNRJALLNS-VJSFXXLFSA-N Synonym: 22,23-dihydrostigmasterol,α-Dihydrofucosterol,24β-Ethylcholesterol,5-Stigmasten-3β-ol,22,23-dihydrostigmasterol,azuprostat,triastonal,cinchol,rhamnol,harzol PubChem CID: 222284 ChEBI: CHEBI:27693 IUPAC Name: (3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol SMILES: CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C
Stigmasterol, 95%, Thermo Scientific Chemicals
CAS: 83-48-7 Molecular Formula: C29H48O Molecular Weight (g/mol): 412.70 MDL Number: MFCD00003630 InChI Key: HCXVJBMSMIARIN-PHZDYDNGSA-N Synonym: stigmasterol,stigmasterin,beta-stigmasterol,stigmasta-5,22-dien-3beta-ol,24s-5,22-stigmastadien-3beta-ol,unii-99wuk5d0y8,stigmasta-5,22e-dien-3beta-ol,stigmasta-5,22-dien-3-beta-ol,3beta,22e-stigmasta-5,22-dien-3-ol,stigmasta-5,22-dien-3-ol, 3b,22e PubChem CID: 5280794 ChEBI: CHEBI:28824 IUPAC Name: (3S,8S,9S,10R,13R,14S,17R)-17-[(E,2R,5S)-5-ethyl-6-methylhept-3-en-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol SMILES: CC[C@H](\C=C\[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)C(C)C
beta-Sitosterol (contains Campesterol) 40.0+%, TCI America™
CAS: 83-46-5 Molecular Formula: C29H50O Molecular Weight (g/mol): 414.718 MDL Number: MFCD00003631 InChI Key: KZJWDPNRJALLNS-VJSFXXLFSA-N Synonym: beta-sitosterol,sitosterol,cupreol,quebrachol,22,23-dihydrostigmasterol,azuprostat,triastonal,cinchol,rhamnol,harzol PubChem CID: 222284 ChEBI: CHEBI:27693 IUPAC Name: (3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol SMILES: CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C
Stigmasterol 90.0+%, TCI America™
CAS: 83-48-7 Molecular Formula: C29H48O Molecular Weight (g/mol): 412.70 MDL Number: MFCD00003630 InChI Key: HCXVJBMSMIARIN-PHZDYDNGSA-N Synonym: stigmasterol,stigmasterin,beta-stigmasterol,stigmasta-5,22-dien-3beta-ol,24s-5,22-stigmastadien-3beta-ol,unii-99wuk5d0y8,stigmasta-5,22e-dien-3beta-ol,stigmasta-5,22-dien-3-beta-ol,3beta,22e-stigmasta-5,22-dien-3-ol,stigmasta-5,22-dien-3-ol, 3b,22e PubChem CID: 5280794 ChEBI: CHEBI:28824 IUPAC Name: (1R,3aS,3bS,7S,9aR,9bS,11aR)-1-[(2R,3E,5S)-5-ethyl-6-methylhept-3-en-2-yl]-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-ol SMILES: CC[C@H](\C=C\[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)C(C)C
Kyfora Bio STEMS (Stigmasterol Hemisuccinate) 1 GR
Stigmasterol hemisuccinate (STEMS) is a stigmasterol derivative that is responsive to changes in pH. Stigmasterol is a naturally occurring phytosterol lipid that is growing in the bioprocessing space for its ability to improve lipid nanoparticle (LNP)-based mRNA transfection efficiency. Conjugation to hemiscuccinate has been shown to improve the cellular uptake in acidic microenvironments, such as those around tumors.Key application(s): LNP, acid-delivery systems
Kyfora Bio Stigmasterol 1 GR
Stigmasterol is a naturally occurring phytosterol lipid that is growing in the bioprocessing space for its ability to improve lipid nanoparticle (LNP) uptake efficiency. LNPs are well known for facilitating the safe and effective delivery of mRNA to target cells, thus enabling therapeutic action. Cholesterol derivatives like stigmasterol offer two major benefits to LNP formulations: they can improve the stability of the LNP and they can increase the cellular uptake efficiency both in cell cultures and in vivo. Kyfora Bio's high purity, transfection grade stigmasterol can be used in conjunction with our other cationic lipid products to provide reliable performance for a variety of bioprocessing applications.Key application(s): LNP, mRNA vaccine
Cayman Chemical StIgmasterol 5g
A natural plant sterol that can be isolated from certain seed oils and herbs, including those used for therapeutic purposes
Medchemexpress LLC Stigmasta-5,22-dien-3-ol, (3β,22E)- | 83-48-7 | 98.5% | 412.69 | 1 G
Stigmasterol is an orally active, immunomodulatory agent with anti-inflammatory and neuroprotective effects. It can cross the blood-brain barrier. It activates AMPK, inhibiting NF-κB and NLRP3 signaling pathways. Stigmasterol reduces microglia-mediated neuroinflammation and alleviates cognitive impairment and Alzheimer's disease. It also regulates M1/M2 polarization of microglia through the TLR4/NF-κB pathway, reducing neuropathic pain.
- Orally active immunomodulatory agent
- Exhibits anti-inflammatory effects
- Neuroprotective properties
- Crosses the blood-brain barrier
- Activates AMPK
- Inhibits NF-κB and NLRP3 signaling pathways
- Reduces microglia-mediated neuroinflammation
- Alleviates cognitive impairment and Alzheimer's disease
- Regulates M1/M2 polarization of microglia
- Reduces neuropathic pain
Medchemexpress LLC HY-N0131 100mg Medchemexpress, Stigmasterol CAS:83-48-7 Purity:>98%
Medchemexpress, HY-N0131 100mg Stigmasterol CAS:83-48-7 Stigmasterol is a plant sterol which has been focused on the cholesterol-lowering activity and is valued as an anti-stiffness factor in the therapy of rheumatic diseases. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Sertraline hydrochloride | 79559-97-0 | 99.9% | 342.69 | 50 MG
Sertraline hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is researched for a number of diseases, such as major depressive disorder and obsessive-compulsive disorder.
- Exhibits spermicidal activity against human spermatozoa.
- Inhibits microglial activation and inflammatory mediator production in vitro.
- Reduces immobility time in the forced swim test in female animals.
- Does not alter spontaneous locomotor activity across various genotypes.
- Shows anti-depression effects in chronic unpredictable mild stress models.